Boc-p-amino-D-Phe(Fmoc)-H is an organic compound whose chemical name is Boc-D-4-[4-(phenyl)] alanine. It is an α-amino acid containing a protecting group Boc(tert-butyloxycarbonyl), wherein the Boc Group protects the amino group and the carboxyl group.
Boc-p-amino-D-Phe(Fmoc)-OH is mainly used in the field of organic synthesis. It is an important intermediate for the synthesis of peptides and can be added to the peptide sequence to regulate the stability and activity of the peptide segment. In addition, it can also be used in drug discovery, Biochemistry and Laboratory research.
A common method for preparing Boc-p-amino-D-Phe(Fmoc)-OH is by Boc protection of 4-(9-fluorenylmethoxycarbonylamino) phenylpropionic acid. The specific preparation method is to react 4-(9-fluorenylmethoxycarbonylamino) phenylpropionic acid with Boc2O(Boc dicarboximide) to generate Boc-D-4-(9-fluorenylmethoxycarbonylamino) phenylpropionic acid, followed by appropriate work-up steps, gives the target product Boc-p-amino-D-Phe(Fmoc)-OH.
Regarding safety information, Boc-p-amino-D-Phe(Fmoc)-OH is a chemical and should be handled with caution. When using, be careful to avoid contact with skin, eyes and mucous membranes, and ensure that the operation is carried out in a well-ventilated laboratory environment. During storage and transportation, contact with oxidants, strong acids, strong bases and other substances should be avoided. Specific safety operations and protective measures can refer to the relevant safety data sheet (SDS) or consult a professional.